The San Francisco 49ers have continued to look like a contender for the NFC West despite all their injuries. Quarterback Brock Purdy has played in only two games this season due to injury; his season stats are 586 passing yards, four touchdowns, and four interceptions. Not great, but he has also been playing with injured receivers, like sophomore receiver Ricky Pearsall. This season, Pearsall has played in only four games, during which he has recorded 20 receptions for 327 yards.
What are the Injury Updates on Brock Purdy and Ricky Pearsall?
Both players have been battling lingering injuries throughout the year, and San Francisco has had to rely on its backups. Christian McCaffrey has carried a large portion of the workload as both a receiver and a rusher, yet the 49ers’ Week 10 matchup against the Los Angeles Rams could pose a challenge.
The Rams rank second in PFSN’s Defensive Impact metrics this season, which will make every offensive possession a challenge for the 49ers, who rank 10th in PFSN’s Offensive Impact metrics.
With that in mind, Thursday’s injury report brought significant updates regarding Purdy and Pearsall ahead of the divisional matchup. Both Purdy and Pearsall showed up on the 49ers’ injury report today.
According to Thursday’s injury report, Purdy was listed with a toe injury and was a limited participant at practice. While it suggests that the injury has healed well, his status will still need to be monitored as the weekend approaches.
Purdy also practiced on Friday, but he is officially listed as questionable for the Week 10 game. However, head coach Kyle Shanahan has confirmed that Mac Jones will get another start. In seven games this season, Jones has thrown for 1,832 yards, 10 touchdowns, and five interceptions.
Pearsall did not participate in practice due to a knee injury. He is officially ruled out for the game against the Rams. His absence is more concerning, as he has been battling injuries throughout the season, and the 49ers opted for a cautious approach by sitting him.
49ers will start Mac Jones at QB vs Rams
OUT
WR Ricky Pearsall
QUESTIONABLE
QB Brock Purdy
DT Alfred Collins
DT Kalia Davis
LB Dee Winters
LB Tatum Bethune
DL Keion White— Cam Inman (@CamInman) November 7, 2025
With Pearsall out this week, the 49ers will rely on George Kittle, Jauan Jennings, and McCaffrey as their primary offensive weapons.